Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.

doi:10.1016/s0022-5347(17)35186-8

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Article

Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.

The Journal of urology - 1 Apr 1994

Brewster S F, Browne S, Brown K W

Abstract excerpt

We present a restriction fragment length polymorphism (RFLP) analysis of 29 benign and 30 malignant prostatic tumors, using polymorphic DNA probes to the putative tumor suppressor genes DCC (Deleted in Colorectal Carcinoma; chromosome 18q21.3), nm23-H1 (17q21.3), APC (Adenomatous Polyposis Coli;...

Topics

Adenocarcinoma
Alleles
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 5
DNA Probes
Genes, APC
Genes, DCC
Genes, Tumor Suppressor
Genes, p53
Heterozygote
Humans
Male
Monomeric GTP-Binding Proteins
NM23 Nucleoside Diphosphate Kinases
Nucleoside-Diphosphate Kinase

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PMID: 7510345
DOI: 10.1016/s0022-5347(17)35186-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7510345-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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