Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer.

Article

Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer.

Cancer research - 15 May 1996

Trybus T M, Burgess A C, Wojno K J, Glover T W, Macoska J A

Abstract excerpt

Utilizing tissue microdissection and PCR techniques, we have examined 35 prostate tumors paired with normal tissues from the same patients for allelic loss at 24 polymorphic loci spanning chromosome 10. Twenty-five tumors (71%) were deleted for at least one chromosome 10 locus. Of the total 35 tu...

Topics

Alleles
Chromosomes, Human, Pair 10
Ethnicity
Gene Deletion
Genetic Markers
Humans
In Situ Hybridization, Fluorescence
Male
Neoplasm Staging
Polymerase Chain Reaction
Prostatic Neoplasms
Tumor Cells, Cultured

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