Article
Serotonin transporter gene and schizophrenia: evidence for association/linkage disequilibrium in families with affected siblings.
Molecular psychiatry - 1 Jan 2000
Hranilovic D, Schwab S G, Jernej B, Knapp M, Lerer B, Albus M, Rietschel M, Kanyas K, Borrmann M, Lichtermann D, Maier W, Wildenauer D B
Abstract excerpt
The serotonergic (5-HT) system has been implicated in the etiopathogenesis of psychoses. Since the 5-HT transporter plays an important role in regulation of 5-HT transmission, its gene can be considered as a candidate for vulnerability to psychiatric disorders. Two polymorphic sites of the 5-HT transporter gene-5-HTTLPR, a VNTR in the 5' regulatory region, and a VNTR in the second intron-were studied in a sample...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
