Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stability of p53 tumor suppressor gene mutations during the process of metastasis and during chemotherapy.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 1996

Taniguchi Y, Gemma A, Takeda Y, Takenaka K, Niitani H, Kudoh S, Shimada T

Abstract excerpt

We analyzed 29 pairs of primary and metastatic lung carcinomas obtained at autopsy for mutations in the p53 gene, using the polymerase chain reaction-single strand conformation polymorphism method (PCR-SSCP). We examined the relationship between p53 gene mutations and the development of metastasis, and the stability of p53 gene mutations during chemotherapy. The tumors consisted of six small cell carcinomas, 13...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Neoplasm
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 8794405
DOI: 10.1016/0169-5002(95)00548-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stability of p53 tumor suppressor gene mutations during the process of metastasis and during chemotherapy.PMID 8794405Read ↗

p53 mutations in primary human lung tumors and their metastases.Semantic proximity Read ↗

[p53 gene abnormalities in advanced primary lung cancer and metastatic tumors].Semantic proximity Read ↗

Alterations of the p53 gene are common and critical events for the maintenance of malignant phenotypes in small-cell lung carcinoma.Semantic proximity Read ↗

Aberrations of the p53 tumor suppressor gene in human non-small cell carcinomas of the lung.Semantic proximity Read ↗

p53 mutations in matched primary and metastatic human tumors.Semantic proximity Read ↗

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.Semantic proximity Read ↗

p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features.Semantic proximity Read ↗

Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer.Semantic proximity Read ↗

p53 gene mutations in primary lung tumors are conserved in brain metastases.Semantic proximity Read ↗

The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution pattern.Semantic proximity Read ↗

Association between p53 mutation and clinicopathological features of non-small cell lung cancer.Semantic proximity Read ↗

p53 mutations do not predict response to paclitaxel in metastatic nonsmall cell lung carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.