Article
Neuroligin 2 is required for synapse development and function at the Drosophila neuromuscular junction.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Jan 2011
Sun Mingkuan, Xing Guanglin, Yuan Liudi, Gan Guangming, Knight David, With Sheila Irene, He Cui, Han Junhai, Zeng Xiankun, Fang Ming, Boulianne Gabrielle L, Xie Wei
Abstract excerpt
Neuroligins belong to a highly conserved family of cell adhesion molecules that have been implicated in synapse formation and function. However, the precise in vivo roles of Neuroligins remain unclear. In the present study, we have analyzed the function of Drosophila neuroligin 2 (dnl2) in synaptic development and function. We show that dnl2 is strongly expressed in the embryonic and larval CNS and at the larval...
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