Article
Neuroligin 4 regulates synaptic growth via the bone morphogenetic protein (BMP) signaling pathway at the Drosophila neuromuscular junction.
The Journal of biological chemistry - 3 Nov 2017
Zhang Xinwang, Rui Menglong, Gan Guangmin, Huang Cong, Yi Jukang, Lv Huihui, Xie Wei
Abstract excerpt
The neuroligin (Nlg) family of neural cell adhesion molecules is thought to be required for synapse formation and development and has been linked to the development of autism spectrum disorders in humans. In Drosophila melanogaster, mutations in the neuroligin 1-3 genes have been reported to induce synapse developmental defects at neuromuscular junctions (NMJs), but the role of neuroligin 4 (dnlg4) in synapse...
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