Article
Cellular analysis of limb development in the mouse mutant hypodactyly.
Developmental genetics - 1 Jan 1996
Robertson K E, Chapman M H, Adams A, Tickle C, Darling S M
Abstract excerpt
The limb defect in the mouse Hypodactyly (Hd) affects only the distal structures. Heterozygotes (Hd/+) lack all or part of the distal phalanx and the terminal claw of digit on the hindlimbs; mice homozygous (Hd/Hd) for the mutation have just one digit on each of the four limbs. Early limb develop...
Topics
- Animals
- Bone and Bones
- Cartilage
- Cell Death
- Cells, Cultured
- Congenital Abnormalities
- Embryo, Mammalian
- Embryonic and Fetal Development
- Female
- Genotype
- Gestational Age
- Hindlimb
- Limb Buds
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Mutant Strains