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Article

Use of exact and adjusted liability scores to detect genes affecting common traits.

Genetic epidemiology - 1 Jan 1995

Goldin L R, Chase G A, King T M, Badner J A, Gershon E S

Abstract excerpt

We used the Haseman-Elston sib-pair test to screen for linkage of markers to genes for disease susceptibility in the simulated data as given in Problem 2 of GAW9. We applied the analysis to the underlying quantitative liability trait (Q1), other covariates of Q1 (Q2-Q4), and the dichotomous affection status trait. In addition, we analyzed the residual Q1 after adjusting for the covariates. Using the sib-pair...

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PMID: 8788006
DOI: 10.1002/gepi.1370120639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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