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Article

Detecting susceptibility genes in case-control studies using set association.

BMC genetics - 31 Dec 2003

Kim Sung, Zhang Kui, Sun Fengzhu

Abstract excerpt

Complex diseases are generally caused by intricate interactions of multiple genes and environmental factors. Most available linkage and association methods are developed to identify individual susceptibility genes assuming a simple disease model blind to any possible gene - gene and gene - environmental interactions. We used a set association method that uses single-nucleotide polymorphism markers to locate...

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Identifiers

PMID: 14975077
DOI: 10.1186/1471-2156-4-S1-S9
PMCID: PMC1866530

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