Article
Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky.
Genetic epidemiology - 1 Jan 2007
Bartlett Christopher W, Vieland Veronica J, Bartlett Jacquelaine, Bell Jordana T, Bhattacharjee Samsiddhi, Clerget-Darpoux Françoise, Bush William S, Edwards Todd L, Gao Guimin, Halder Indrani, Huang Yungui, Kotti Salma, Larkin Emma K, Li Hua, Motsinger Alison A, Mukhopadhyay Nandita, Namkung Junghyun, Park Taesung, Ritchie Marylyn D, Stein Catherine M, Zhou Ji-Yuan
Abstract excerpt
Interest in mapping susceptibility alleles for complex diseases, which do not follow a classic single-gene segregation pattern, has driven interest in methods that account for, or use information from one locus when mapping another. Our discussion group examined methods related to epistasis or gene x gene interaction. The goal of modeling gene x gene interaction varied across groups; some papers tried to detect...
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