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Article

Use of sibling risk ratios and components of genetic variance in the characterization of a simulated oligogenic disease.

Genetic epidemiology - 1 Jan 1995

Almasy L, Tierney C, Risch N

Abstract excerpt

Sibling risk ratios are used to quantify the genetic effect of two simulated disease loci, identified through TDT and association methods and characterized via components of variance derived from a relative penetrance matrix. Inconsistencies between the data set and the simulating model are also discussed.

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Identifiers

PMID: 8787974
DOI: 10.1002/gepi.1370120607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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