Analysis of quantitative risk factors for a common oligogenic disease.

doi:10.1002/gepi.1370120638

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Article

Analysis of quantitative risk factors for a common oligogenic disease.

Genetic epidemiology - 1 Jan 1995

Goddard K A, Jarvik G P, Graham J, McNeney B, Hsu L, Siegmund K, Grosser S, Olson J, Wijsman E M

Abstract excerpt

All three simulated loci influencing the quantitative variables Q1, Q2 and Q3 were successfully mapped by using a strategy of covariate adjustment and segregation analysis, coupled with association analyses and lod-score analyses.

Topics

Chromosome Mapping
Genetic Diseases, Inborn
Genetic Markers
Genetic Testing
Genome, Human
Humans
Linear Models
Linkage Disequilibrium
Lod Score
Phenotype
Risk Factors

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