Article
Weighted pairwise correlation and transmission disequilibrium in a common oligogenic disease.
Genetic epidemiology - 1 Jan 1995
Corder E H
Abstract excerpt
Weighted pairwise correlation (WPC) linkage analysis and the transmission disequilibrium test (TDT) for allelic association were applied to simulated family data for a common oligogenic disorder in order to localize genes that increase levels of Q1. Preliminary linear models indicated that Q1 inc...
Topics
- Alleles
- Case-Control Studies
- Computer Simulation
- Data Interpretation, Statistical
- Genetic Diseases, Inborn
- Humans
- Linear Models
- Linkage Disequilibrium
- Models, Genetic