Article
Weighted pairwise correlation and transmission disequilibrium in a common oligogenic disease.
Genetic epidemiology - 1 Jan 1995
Corder E H
Abstract excerpt
Weighted pairwise correlation (WPC) linkage analysis and the transmission disequilibrium test (TDT) for allelic association were applied to simulated family data for a common oligogenic disorder in order to localize genes that increase levels of Q1. Preliminary linear models indicated that Q1 increases with age, Q2, Q3, and the occurrence of D5G28 allele 3 (D5G28(3). WPC provided evidence for linkage of Q1 to...
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