Empirical affected-sib-pair statistics: two simulation strategies.

doi:10.1002/(SICI)1098-2272(1997)14:6<1073::AID-GEPI85>3.0.CO;2-E

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Article

Empirical affected-sib-pair statistics: two simulation strategies.

Genetic epidemiology - 1 Jan 1997

Dina C, Buzzi J C, Demenais F, Martinez M

Abstract excerpt

We compare two simulation procedures used to determine empirical distributions of three affected sib-pair test-statistics in family samples with missing parental marker information. P1 and P2 procedures differ according to whether affected sibs' genotypes are ignored (P1) or accounted for (P2) to...

Topics

Computer Simulation
Female
Genetic Linkage
Genetic Markers
Genotype
Heterozygote
Humans
Male
Matched-Pair Analysis
Nuclear Family
Parents

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