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Article

Evidence that MSL-mediated dosage compensation in Drosophila begins at blastoderm.

Development (Cambridge, England) - 1 Sept 1996

Franke A, Dernburg A, Bashaw G J, Baker B S

Abstract excerpt

In Drosophila equalization of the amounts of gene products produced by X-linked genes in the two sexes is achieved by hypertranscription of the single male X chromosome. This process, dosage compensation, is controlled by a set of male-specific lethal (msl) genes, that appear to act at the level of chromatin structure. The properties of the MSL proteins have been extensively studied in the polytene salivary gland...

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Identifiers

PMID: 8787749
DOI: 10.1242/dev.122.9.2751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence that MSL-mediated dosage compensation in Drosophila begins at blastoderm.PMID 8787749Read ↗

Dosage compensation in Drosophila: the X-chromosomal binding of MSL-1 and MLE is dependent on Sxl activity.Semantic proximity Read ↗

Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila.Semantic proximity Read ↗

Role of the male specific lethal (msl) genes in modifying the effects of sex chromosomal dosage in Drosophila.Semantic proximity Read ↗

Gene expression analysis of the function of the male-specific lethal complex in Drosophila.Semantic proximity Read ↗

Sex-specific regulation of the male-specific lethal-1 dosage compensation gene in Drosophila.Semantic proximity Read ↗

Regulation of the sex-specific binding of the maleless dosage compensation protein to the male X chromosome in Drosophila.Semantic proximity Read ↗

Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila.Semantic proximity Read ↗

Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation.Semantic proximity Read ↗

Modulation of Heterochromatin by Male Specific Lethal Proteins and roX RNA in Drosophila melanogaster Males.Semantic proximity Read ↗

RNA-dependent association of the Drosophila maleless protein with the male X chromosome.Semantic proximity Read ↗

Primary Sex Determination in Drosophila melanogaster Does Not Rely on the Male-Specific Lethal Complex.Semantic proximity Read ↗

Drosophila maleless gene counteracts X global aneuploid effects in males.Semantic proximity Read ↗

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