Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An RNase P RNA subunit mutation affects ribosomal RNA processing.

Nucleic acids research - 15 Aug 1996

Chamberlain J R, Pagán-Ramos, Kindelberger D W, Engelke D R

Abstract excerpt

RNase P is a ribonucleoprotein endoribonuclease responsible for the 5' maturation of precursor tRNAs in all organisms. While analyzing mutations in conserved positions of the yeast nuclear RNase P RNA subunit, significant accumulation of an aberrant RNA of approximately 193 nucleotides was observed. This abundant RNA was identified as a 3'extended form of the 5.8S rRNA. This strain also displays a slightly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Molecular Sequence Data
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to RNA Precursors

Share to RNA Processing, Post-Transcriptional

Share to RNA, Ribosomal

Share to Saccharomyces cerevisiae

Share to Substrate Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 8774895
DOI: 10.1093/nar/24.16.3158
PMCID: PMC146068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An RNase P RNA subunit mutation affects ribosomal RNA processing.PMID 8774895Read ↗

RNase MRP is required for entry of 35S precursor rRNA into the canonical processing pathway.Semantic proximity Read ↗

Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genome-wide search for yeast RNase P substrates reveals role in maturation of intron-encoded box C/D small nucleolar RNAs.Semantic proximity Read ↗

Processing of the yeast pre-rRNA at sites A(2) and A(3) is linked.Semantic proximity Read ↗

The 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site.Semantic proximity Read ↗

An essential protein-binding domain of nuclear RNase P RNA.Semantic proximity Read ↗

Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae.Semantic proximity Read ↗

Characterization of conserved sequence elements in eukaryotic RNase P RNA reveals roles in holoenzyme assembly and tRNA processing.Semantic proximity Read ↗

Mutational analysis of the RNA component of Saccharomyces cerevisiae RNase MRP reveals distinct nuclear phenotypes.Semantic proximity Read ↗

The RNA catabolic enzymes Rex4p, Rnt1p, and Dbr1p show genetic interaction with trans-acting factors involved in processing of ITS1 in Saccharomyces cerevisiae pre-rRNA.Semantic proximity Read ↗

A new rRNA processing mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

Deletions in the S1 domain of Rrp5p cause processing at a novel site in ITS1 of yeast pre-rRNA that depends on Rex4p.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.