Article
Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae.
RNA (New York, N.Y.) - 1 Aug 2011
Marvin Michael C, Clauder-Münster Sandra, Walker Scott C, Sarkeshik Ali, Yates John R, Steinmetz Lars M, Engelke David R
Abstract excerpt
Ribonuclease P (RNase P) is an essential endoribonuclease that catalyzes the cleavage of the 5' leader of pre-tRNAs. In addition, a growing number of non-tRNA substrates have been identified in various organisms. RNase P varies in composition, as bacterial RNase P contains a catalytic RNA core and one protein subunit, while eukaryotic nuclear RNase P retains the catalytic RNA but has at least nine protein...
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