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Article

Characterization of conserved sequence elements in eukaryotic RNase P RNA reveals roles in holoenzyme assembly and tRNA processing.

RNA (New York, N.Y.) - 1 Jun 2005

Xiao Shaohua, Day-Storms Jeremy J, Srisawat Chatchawan, Fierke Carol A, Engelke David R

Abstract excerpt

RNase P is a ubiquitous endoribonuclease responsible for cleavage of the 5' leader of precursor tRNAs (pre-tRNAs). Although the protein composition of RNase P holoenzymes varies significantly among Bacteria, Archaea, and Eukarya, the holoenzymes have essential RNA subunits with several sequences and structural features that are common to all three kingdoms of life. Additional structural elements of the RNA...

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Identifiers

PMID: 15872187
DOI: 10.1261/rna.7282205
PMCID: PMC1370773

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Source receipt: pubmed, retrieved 7 Sept 2026.

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