Article
p53 protein expression and gene analysis in clear cell adenocarcinoma of the vagina and cervix.
Gynecologic oncology - 1 Mar 1996
Waggoner S E, Anderson S M, Luce M C, Takahashi H, Boyd J
Abstract excerpt
OBJECTIVE: p53 is the most commonly mutated gene in human cancers. The objective of this study was to determine if clear cell adenocarcinomas (CCAs) of the vagina and cervix are associated with p53 gene mutations or alterations in p53 tumor-suppressor protein expression. METHODS: Paraffin-embedded tissue specimens from 21 women (median age 22 years) with clear cell adenocarcinoma of the vagina or cervix were...
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