Article
p53 tumor suppressor gene protein expression in cervical cancer: relationship to prognosis.
European journal of obstetrics, gynecology, and reproductive biology - 1 Nov 1995
Bremer G L, Tieboschb A T, van der Putten H W, de Haan J, Arends J W
Abstract excerpt
OBJECTIVE: Mutation of the p53 gene can be found in several human tumors. We tested the hypothesis whether overexpression of p53 protein is a parameter of more aggressive disease in patients with cervical cancer. STUDY DESIGN: In this study, we describe the effects of p53 overexpression in 156 patients with cervical cancer (Figo stage IB-IV) by assessing expression patterns of the p53 gene product using a...
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