p53 tumor suppressor gene protein expression in cervical cancer: relationship to prognosis.

doi:10.1016/0301-2115(95)02225-v

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Article

p53 tumor suppressor gene protein expression in cervical cancer: relationship to prognosis.

European journal of obstetrics, gynecology, and reproductive biology - 1 Nov 1995

Bremer G L, Tieboschb A T, van der Putten H W, de Haan J, Arends J W

Abstract excerpt

OBJECTIVE: Mutation of the p53 gene can be found in several human tumors. We tested the hypothesis whether overexpression of p53 protein is a parameter of more aggressive disease in patients with cervical cancer. STUDY DESIGN: In this study, we describe the effects of p53 overexpression in 156 pa...

Topics

Antibodies, Monoclonal
Female
Gene Expression
Genes, p53
Humans
Lymph Nodes
Lymphatic Metastasis
Mutation
Neoplasm Staging
Prognosis
Survival Rate
Uterine Cervical Neoplasms

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