Molecular genetic analysis of clear cell adenocarcinomas of the vagina and cervix associated and unassociated with diethylstilbestrol exposure in utero

Abstract excerpt

BACKGROUND: Prenatal exposure to the synthetic estrogen diethylstilbestrol (DES) is associated with the subsequent development of clear cell adenocarcinoma of the lower reproductive tract in young women, and data concerning the molecular genetic alterations involved in the etiology of this tumor type have not previously been reported. Such knowledge would be of potential value by providing insight into the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer Risks and Factors
• Share to Carcinogens and Genotoxicity Assessment
• Share to Effects and risks of endocrine disrupting chemicals