Article
Overexpression of p53 and absent genetic mutation in clear cell chondrosarcoma.
International journal of oncology - 1 Aug 2001
Park Y K, Park H R, Chi S G, Ushigome S, Unni K K
Abstract excerpt
Clear cell chondrosarcoma is one of the extremely rare chondrosarcomas. The pathogenesis and the molecular genetic events, which contribute to the development of clear cell chondrosarcoma, are not well elucidated, due in part to the lack of sufficient tumor tissue available. To characterize the involvement of the p53 gene abnormality in this disease, we analyzed expression and sequence alteration of p53 by...
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