Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects.

doi:10.1212/wnl.50.2.355

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Article

Apolipoprotein E genotype influences cognitive 'phenotype' in patients with Alzheimer's disease but not in healthy control subjects.

Neurology - 1 Feb 1998

Smith G E, Bohac D L, Waring S C, Kokmen E, Tangalos E G, Ivnik R J, Petersen R C

Abstract excerpt

We examined the association of apolipoprotein E (apo E) genotype with cognitive performance in Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) patients and in normal subjects. One hundred fifty-seven AD patients, 35 MCI patients who developed AD during longitudinal follow-up, and 341 normal control subjects from the Mayo Clinic Alzheimer's Disease Patient Registry were studied. All participants were...

Topics

Aged
Alleles
Alzheimer Disease
Apolipoproteins E
Attention
Cognition
Cognition Disorders
Confidence Intervals
Female
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Learning

Male

Memory

Perception

Phenotype

Polymerase Chain Reaction

Reference Values

Source

Open in PubMed

Identifiers

PMID: 9484353
DOI: 10.1212/wnl.50.2.355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9484353-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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