Article
Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Sept 1996
Adams A K, Holm C
Abstract excerpt
To investigate the relationship between the DNA replication apparatus and the control of telomere length, we examined the effects of several DNA replication mutations on telomere length in Saccharomyces cerevisiae. We report that a mutation in the structural gene for the large subunit of DNA replication factor C (cdc44/rfc1) causes striking increases in telomere length. A similar effect is seen with mutations in...
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