Article
The large subunit of replication factor C (Rfc1p/Cdc44p) is required for DNA replication and DNA repair in Saccharomyces cerevisiae.
Genetics - 1 Jan 1996
McAlear M A, Tuffo K M, Holm C
Abstract excerpt
We used genetic and biochemical techniques to characterize the phenotypes associated with mutations affecting the large subunit of replication factor C (Cdc44p or Rfc1p) in Saccharomyces cerevisiae. We demonstrate that Cdc44p is required for both DNA replication and DNA repair in vivo. Cold-sensi...
Topics
- Base Sequence
- Cell Cycle
- DNA Damage
- DNA Primers
- DNA Repair
- DNA Replication
- DNA, Fungal
- DNA-Binding Proteins
- Homeodomain Proteins
- Minor Histocompatibility Antigens
- Molecular Sequence Data
- Mutation
- Phenotype
- Protein Conformation
- Proto-Oncogene Proteins c-bcl-2
- Replication Protein C
- Repressor Proteins
- Saccharomyces cerevisiae