Article
Retained cocaine conditioned place preference in D1 receptor deficient mice.
Neuroreport - 27 Nov 1995
Miner L L, Drago J, Chamberlain P M, Donovan D, Uhl G R
Abstract excerpt
The role of the D1 dopamine receptor subtype in mediating cocaine effects was examined in mice in which the D1 receptor gene had been ablated by homologous recombination. Cocaine reward was assessed by conditioned place preference experiments using mice which had either one allele (+/-) or both alleles (-/-) of the D1 dopamine receptor gene disrupted and in their wild type (+/+) littermates. Cocaine conditioning...
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