Article
Dopamine D3 receptor knockout mice and the motivational effects of ethanol.
Pharmacology, biochemistry, and behavior - 1 May 2003
Boyce-Rustay Janel M, Risinger Fred O
Abstract excerpt
Dopamine D3 receptors have been implicated in the behavioral effects of abused drugs including ethanol. The present experiments characterized the acquisition of ethanol-induced place conditioning and ethanol self-administration in D3 knockout (D3 KO) mice compared with C57BL/6J (C57) mice. For place conditioning, D3 KO and C57 mice received six pairings of a tactile stimulus with ethanol (3 g/kg i.p.). D3 KO mice...
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