Article
Dopamine receptors and dopamine transporter in brain function and addictive behaviors: insights from targeted mouse mutants.
Developmental neuroscience - 1 Jan 1998
Drago J, Padungchaichot P, Accili D, Fuchs S
Abstract excerpt
Recent advances in molecular biology have resulted in a number of genetically manipulated mice with defined changes at dopamine receptor and the dopamine transporter (DAT) loci. Mice with targeted mutations at the D1 receptor (D1R) are growth-retarded and show downregulated expression of dynorphi...
Topics
- Animals
- Behavior, Addictive
- Brain
- Carrier Proteins
- Dopamine Plasma Membrane Transport Proteins
- Gene Targeting
- Membrane Glycoproteins
- Membrane Transport Proteins
- Mice
- Mutation
- Nerve Tissue Proteins
- Receptors, Dopamine