Article
Murine genotype influences the specificity, magnitude and persistence of murine mercury-induced autoimmunity.
Journal of autoimmunity - 1 Apr 1996
Hultman P, Turley S J, Eneström S, Lindh U, Pollard K M
Abstract excerpt
Genetic factors are major contributors in determining the susceptibility to systemic autoimmune diseases. We studied the influence of genotype on systemic autoimmunity by treating female mice of the H-2s strains SJL/N, SJL/J, A.SW, and B10.S with mercuric chloride (HgCl2) for 10 weeks and then following autoantibody and tissue immune deposits during the subsequent 12 months. All strains developed antinucleolar...
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