Article
Murine genotype influences the specificity, magnitude and persistence of murine mercury-induced autoimmunity.
Journal of autoimmunity - 1 Apr 1996
Hultman P, Turley S J, Eneström S, Lindh U, Pollard K M
Abstract excerpt
Genetic factors are major contributors in determining the susceptibility to systemic autoimmune diseases. We studied the influence of genotype on systemic autoimmunity by treating female mice of the H-2s strains SJL/N, SJL/J, A.SW, and B10.S with mercuric chloride (HgCl2) for 10 weeks and then fo...
Topics
- Animals
- Antibodies, Antinuclear
- Antibody Specificity
- Antigen-Antibody Complex
- Autoimmune Diseases
- Chromosomal Proteins, Non-Histone
- Enzyme-Linked Immunosorbent Assay
- Female
- Fluorescent Antibody Technique, Indirect
- Genotype
- H-2 Antigens
