Article
Experimental studies on genetically determined susceptibility to mercury-induced autoimmune response.
Renal failure - 1 Jan 2000
Nielsen J B, Hultman P
Abstract excerpt
Individual differences in susceptibility may be caused by genetical as well as external variables. In mice as well as rats, autoimmune response can be induced by mercury or gold. The present data demonstrates that the autoimmune response depends qualitatively on the H-2 haplotype. If a strain of mice does not have the susceptible haplotype, no autoimmunity will be induced. However, even among the responding...
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