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Article

Mercury-induced autoimmunity in mice.

Environmental health perspectives - 1 Oct 2002

Nielsen Jesper Bo, Hultman Per

Abstract excerpt

We have studied the effect of gender, genetics, and toxicokinetics on immune parameters in mercury-induced autoimmunity in mice. Data strongly suggest that the mechanism for mercury-induced autoimmunity involves modification of the autoantigen fibrillarin by mercury followed by a T-cell-dependent immune response driven by the modified fibrillarin. Mice with different H-2 haplotypes were treated with (203)HgCl(2)...

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Identifiers

PMID: 12426151
DOI: 10.1289/ehp.02110s5877
PMCID: PMC1241265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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