Article
Effects of the murine genotype on T cell activation and cytokine production in murine mercury-induced autoimmunity.
Journal of autoimmunity - 1 Aug 1997
Johansson U, Sander B, Hultman P
Abstract excerpt
Mercury induces a systemic autoimmune condition characterized by auto-antibodies to the nucleolar protein fibrillarin (AFA) and systemic immune-complex (IC) deposits in genetically susceptible mouse strains. This study examines T cell activation and cytokine production following mercury exposure in genetically susceptible and resistant strains. Mercury injected s.c., according to the protocol for induction of...
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