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Article

Venous thrombosis: factor V G1691A genotyping related to APC resistance as measured by 2 methods.

European journal of haematology - 1 Apr 1997

Alderborn A, Siegbahn A, Wadelius C

Abstract excerpt

Blood samples were collected from consecutive unrelated patients with venous thrombosis. The patients originate from the middle part of Sweden. We investigated the presence of the reported point mutation at nt 1691 of factor V which renders the protein resistant to cleavage by activated protein C (APC). Thirty-seven per cent of the patients were heterozygote carriers, and 4.5% were homozygotes for a mutated...

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Source

Identifiers

PMID: 9186532
DOI: 10.1111/j.1600-0609.1997.tb01659.x

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Venous thrombosis: factor V G1691A genotyping related to APC resistance as measured by 2 methods.PMID 9186532Read ↗

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[Activated protein C resistance and factor V Leiden: clinical interest].Semantic proximity Read ↗

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Detection of a common mutation in factor V gene responsible for resistance to activate protein C causing predisposition to thrombosis.Semantic proximity Read ↗

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