Article
T-cell receptors: germline polymorphism and patterns of usage in demyelinating diseases.
Critical reviews in immunology - 1 Jan 1992
Usuku K, Joshi N, Hauser S L
Abstract excerpt
The genomic organization of the T-cell receptor (TCR) gene complexes accounts for many central aspects of T-cell immunobiology, including specificity and diversity. Recent data indicate that polymorphism of TCR genes is present within a species and may influence the immune phenotype of an individual. Such polymorphism has been detected by RFLP, by the presence of large regions of insertion or deletion of germline...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
