T-cell receptors: germline polymorphism and patterns of usage in demyelinating diseases.

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Article

T-cell receptors: germline polymorphism and patterns of usage in demyelinating diseases.

Critical reviews in immunology - 1 Jan 1992

Usuku K, Joshi N, Hauser S L

Abstract excerpt

The genomic organization of the T-cell receptor (TCR) gene complexes accounts for many central aspects of T-cell immunobiology, including specificity and diversity. Recent data indicate that polymorphism of TCR genes is present within a species and may influence the immune phenotype of an individ...

Topics

Alleles
Animals
Autoimmune Diseases
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 7
Demyelinating Diseases
Encephalomyelitis, Autoimmune, Experimental
Gene Rearrangement, T-Lymphocyte
Humans
Mice
Multiple Sclerosis
Myelin Basic Protein
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Prevalence
Receptors, Antigen, T-Cell

Source

Open in PubMed

Identifiers

PMID: 1382445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1382445-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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