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Article

Genetic predisposition to autoimmunity--what have we learned?

Seminars in immunology - 1 Apr 2011

Rai Ekta, Wakeland Edward K

Abstract excerpt

Rapid advances in genetic technologies have led to the identification of more than 85 loci that contribute to susceptibility to autoimmune diseases. These susceptibility genes are distributed throughout the innate and adaptive immune systems, indicating that dysregulations in both immune systems participate in the development of autoimmunity. A significant subset of these susceptibility genes are shared between...

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PMID: 21288738
DOI: 10.1016/j.smim.2011.01.015

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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