Homologous recombination in variants of the B16 murine melanoma with reference to their metastatic potential.

Abstract excerpt

Genomic instability has been accepted as providing a phenotypic variety of malignant cells within a developing tumour. Defects in genetic recombination can often lead to phenotypic differences; therefore, it is possible that metastatic variant cell lines exhibit their particular phenotype as a result of an altered ability to catalyse homologous recombination. We have investigated recombination efficiency in B16...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blotting, Southern
• Share to Cloning, Molecular
• Share to Genetic Variation