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Article

Predominance of the metastatic phenotype in somatic cell hybrids of the K-1735 murine melanoma.

Cancer research - 1 Dec 1991

Staroselsky A H, Pathak S, Chernajovsky Y, Tucker S L, Fidler I J

Abstract excerpt

The purpose of these studies was to determine whether the metastatic phenotype will dominate when metastatic and nonmetastatic clones of the K-1735 mouse melanoma are hybridized by somatic cell fusion. Three nonmetastatic and three metastatic clones were transfected with DNA from plasmids pSV2neo or pSV2hygro, which confer resistance to the drugs neomycin or hygromycin, respectively. The metastatic properties of...

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PMID: 1834329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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