Article
Pleiotropic effects of mutations at positions 13 and 914 in Escherichia coli 16S ribosomal RNA.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 2000
Brakier-Gingras L, Pinard R, Dragon F
Abstract excerpt
Mutations at position 13 or 914 of Escherichia coli 16S ribosomal RNA exert pleiotropic effects on protein synthesis. They interfere with the binding of streptomycin, a translational miscoding drug, to the ribosomes. They increase translational fidelity, and this effect can be related to a pertur...
Topics
- Base Sequence
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Phenotype
- RNA, Bacterial
- RNA, Ribosomal, 16S
- Streptomycin