Article
Error-prone and error-restrictive mutations affecting ribosomal protein S12.
Journal of molecular biology - 1 Jul 2011
Agarwal Deepali, Gregory Steven T, O'Connor Michael
Abstract excerpt
Ribosomal protein S12 plays a pivotal role in decoding functions on the ribosome. X-ray crystallographic analyses of ribosomal complexes have revealed that S12 is involved in the inspection of codon-anticodon pairings in the ribosomal A site, as well as in the succeeding domain rearrangements of the 30S subunit that are essential for accommodation of aminoacyl-tRNA. A role for S12 in tRNA selection is also well...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
