Article
Positions 13 and 914 in Escherichia coli 16S ribosomal RNA are involved in the control of translational accuracy.
Nucleic acids research - 25 Feb 1994
Pinard R, Côté M, Payant C, Brakier-Gingras L
Abstract excerpt
Using a conditional expression system with the temperature-inducible lambda PL promoter, we previously showed that the single mutations 13U-->A and 914A-->U, and the double mutation 13U-->A and 914A-->U in Escherichia coli 16S ribosomal RNA impair the binding of streptomycin (Pinard et al., The FASEB Journal, 1993, 7, 173-176). In this study, we found that the two single mutations and the double mutation increase...
Topics
- Base Sequence
- Cell Division
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Oligonucleotide Probes
- Protein Biosynthesis
- RNA, Bacterial
- RNA, Ribosomal, 16S