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Article

Contribution of 16S rRNA nucleotides forming the 30S subunit A and P sites to translation in Escherichia coli.

RNA (New York, N.Y.) - 1 Nov 2005

Abdi Nimo M, Fredrick Kurt

Abstract excerpt

Many contacts between the ribosome and its principal substrates, tRNA and mRNA, involve universally conserved rRNA nucleotides, implying their functional importance in translation. Here, we measure the in vivo translation activity conferred by substitution of each 16S rRNA base believed to contribute to the A or P site. We find that the 30S P site is generally more tolerant of mutation than the 30S A site. In the...

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Identifiers

PMID: 16177132
DOI: 10.1261/rna.2118105
PMCID: PMC1370848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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