Article
Capped mRNA degradation intermediates accumulate in the yeast spb8-2 mutant.
Molecular and cellular biology - 1 Sept 1998
Boeck R, Lapeyre B, Brown C E, Sachs A B
Abstract excerpt
mRNA in the yeast Saccharomyces cerevisiae is primarily degraded through a pathway that is stimulated by removal of the mRNA cap structure. Here we report that a mutation in the SPB8 (YJL124c) gene, initially identified as a suppressor mutation of a poly(A)-binding protein (PAB1) gene deletion, s...
Topics
- Amino Acid Sequence
- Fungal Proteins
- Gene Deletion
- Genotype
- Kinetics
- Molecular Sequence Data
- Open Reading Frames
- Plasmids
- Poly(A)-Binding Proteins
- RNA Cap-Binding Proteins
- RNA Caps
- RNA, Fungal
- RNA, Messenger
- RNA-Binding Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Alignment
- Sequence Homology, Amino Acid