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Article

The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast.

RNA (New York, N.Y.) - 1 Jun 2003

Baron-Benhamou Julie, Fortes Puri, Inada Toshifumi, Preiss Thomas, Hentze Matthias W

Abstract excerpt

In eukaryotes, the m(7)GpppN cap structure is added to all nascent RNA polymerase II transcripts, and serves important functions at multiple steps of RNA metabolism. The predominantly nuclear cap-binding complex (CBC) binds to the cap during RNA synthesis. The predominantly cytoplasmic eukaryotic initiation factor 4F (eIF4F) is thought to replace CBC after export of mature mRNA to the cytoplasm, and mediates the...

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Identifiers

PMID: 12756324
DOI: 10.1261/rna.5100903
PMCID: PMC1370433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast.PMID 12756324Read ↗

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General RNA binding proteins render translation cap dependent.Semantic proximity Read ↗

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