Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship of HIV-1 envelope V2 and V3 sequences of the primary isolates to the viral phenotype.

Microbiology and immunology - 1 Jan 1996

Yoshimura K, Matsushita S, Hayashi A, Takatsuki K

Abstract excerpt

We examined the relationship between the amino acid sequences of the V2 and V3 regions of the envelope protein and the biological properties of ten human immunodeficiency virus type 1 (HIV-1) primary isolates. The infectivity, cytopathic effect (CPE), and syncytium forming activity of these prima...

Topics

Adolescent
Adult
Amino Acid Sequence
Base Sequence
Female
HIV-1
Humans
Male
Middle Aged
Molecular Sequence Data
Phenotype
RNA, Viral
Sequence Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Envelope Proteins

Source

Identifiers

PMID: 8709863
DOI: 10.1111/j.1348-0421.1996.tb03347.x

Genes

CPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8709863-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship of HIV-1 envelope V2 and V3 sequences of the primary isolates to the viral phenotype.PMID 8709863Read ↗

Syncytium induction in primary CD4+ T-cell lines from normal donors by human immunodeficiency virus type 1 isolates with non-syncytium-inducing genotype and phenotype in MT-2 cells.Semantic proximity Read ↗

V3 loop sequence analysis of seven HIV type 1 group O isolates phenotyped in peripheral blood mononuclear cells and MT-2 cells.Semantic proximity Read ↗

Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates.Semantic proximity Read ↗

Progression to AIDS in macaques is associated with changes in the replication, tropism, and cytopathic properties of the simian immunodeficiency virus variant population.Semantic proximity Read ↗

The V1/V2 Region of Human Immunodeficiency Virus Type 1 Modulates the Sensitivity to Neutralization by Soluble CD4 and Cellular TropismSemantic proximity Read ↗

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule.Semantic proximity Read ↗

Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution.Semantic proximity Read ↗

The cytopathicity of a simian immunodeficiency virus Mne variant is determined by mutations in Gag and Env.Semantic proximity Read ↗

Five human immunodeficiency virus type 1 phenotypic variants with different MT-2 cell tropisms correlate with prognostic markers of disease.Semantic proximity Read ↗

Mapping of independent V3 envelope determinants of human immunodeficiency virus type 1 macrophage tropism and syncytium formation in lymphocytesSemantic proximity Read ↗

Relationship between the V3 loop and the phenotypes of human immunodeficiency virus type 1 (HIV-1) isolates from children perinatally infected with HIV-1.Semantic proximity Read ↗

Syncytium-inducing and non-syncytium-inducing capacity of human immunodeficiency virus type 1 subtypes other than B: phenotypic and genotypic characteristics. WHO Network for HIV Isolation and Characterization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.