Article
V3 loop sequence analysis of seven HIV type 1 group O isolates phenotyped in peripheral blood mononuclear cells and MT-2 cells.
AIDS research and human retroviruses - 1 Nov 1996
De Jong J, Simon F, Van der Groen G, Baan E, Saragosti S, Brun-Vézinet F, Goudsmit J
Abstract excerpt
HIV-1-infected individuals from which syncytium-inducing (SI) viruses are isolated most often progress more rapidly to AIDS than individuals carrying only non-syncytium-inducing (NSI) viruses. The syncytium-inducing capacity of virus isolates is commonly determined in conjunction to replication in MT-2 cells. Comparison of HIV-1 env sequences and a site-directed mutagenesis study have indicated that the presence...
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