Relationship between the V3 loop and the phenotypes of human immunodeficiency virus type 1 (HIV-1) isolates from children perinatally infected with HIV-1.

doi:10.1128/JVI.69.1.82-92.1995

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Article

Relationship between the V3 loop and the phenotypes of human immunodeficiency virus type 1 (HIV-1) isolates from children perinatally infected with HIV-1.

Journal of virology - 1 Jan 1995

Mammano F, Salvatori F, Ometto L, Panozzo M, Chieco-Bianchi L, De Rossi A

Abstract excerpt

The third variable region (V3) of the envelope protein of human immunodeficiency virus type 1 (HIV-1) contains group- and type-specific epitopes for neutralizing antibodies and contains determinants involved in viral tropism and syncytium-inducing (SI) activity. We studied the in vivo relationship between V3 sequences and viral phenotypes in 24 perinatally HIV-1-infected children. To avoid in vitro selection of...

Topics

Amino Acid Sequence
Cell Line
Child
Child, Preschool
Consensus Sequence
Epitopes
HIV Envelope Protein gp120
HIV Infections
HIV-1
Humans
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Monocytes

Neutralization Tests

Peptide Fragments

Phenotype

Sequence Homology, Amino Acid

T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 7527089
DOI: 10.1128/JVI.69.1.82-92.1995
PMCID: PMC188551

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7527089-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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