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Article

The cytopathicity of a simian immunodeficiency virus Mne variant is determined by mutations in Gag and Env.

Journal of virology - 1 Oct 1997

Kimata J T, Overbaugh J

Abstract excerpt

Previous studies suggested that the rapidly replicating, highly cytopathic, syncytium-inducing (rapid-high/SI) phenotype of simian immunodeficiency virus Mne variants that evolved in macaques inoculated with a slowly replicating, minimally cytopathic, non-syncytium-inducing (slow-low/NSI) molecular clone was not solely the result of changes in the envelope surface protein (Env SU). To define the viral...

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Identifiers

PMID: 9311845
DOI: 10.1128/JVI.71.10.7629-7639.1997
PMCID: PMC192112

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