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Article

Extracellular matrix is a source of mitogenically active platelet-derived growth factor.

Journal of cellular physiology - 1 Aug 1996

Field S L, Khachigian L M, Sleigh M J, Yang G, Vandermark S E, Hogg P J, Chesterman C N

Abstract excerpt

Platelet-derived growth factor (PDGF) is a chemotactic and mitogenic agent for fibroblasts and smooth muscle cells and plays a key role in the development of atherosclerotic lesions. PDGF is produced by a number of normal and transformed cell types and occurs as homo- or heterodimers of A and B polypeptide chains. Using Chinese hamster ovary (CHO) cells transfected with various forms of PDGF, we have previously...

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Identifiers

PMID: 8707868
DOI: 10.1002/(SICI)1097-4652(199608)168:2<322::AID-JCP11>3.0.CO;2-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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