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Article

Autocrine growth stimulation of human meningioma cells by platelet-derived growth factor

1 May 1996

Abstract excerpt

The authors have previously shown that meningioma-derived conditioned medium profoundly stimulates the in vitro proliferation of meningioma cells. In this paper, self mitogenic agents found in the conditioned medium-autocrine growth-stimulatory factors actually secreted by human meningioma cells-are characterized as proteins related to the B chain of platelet-derived growth factor (PDGF) and possibly to the A...

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Identifiers

PMID: 8622161
DOI: 10.3171/jns.1996.84.5.0852

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