Article
Ubiquitination of the yeast a-factor receptor.
The Journal of cell biology - 1 Aug 1996
Roth A F, Davis N G
Abstract excerpt
The a-factor receptor (Ste3p) is one of two pheromone receptors in the yeast Saccharomyces cerevisiae that enable the cell-cell communication of mating. In this report, we show that this receptor is subject to two distinct covalent modifications-phosphorylation and ubiquitination. Phosphorylation, evident on the unstimulated receptor, increases upon challenge by the receptor's ligand, a-factor. We suggest that...
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